Of course, there is no current information on Hepsera, so I will have to do a theoretical evaluation. Since Hepsera is a nucleotide analog, it probably has a very large molecular size which would mean only a very small amount would get through to the breast milk. Secondly, the mothers plasma level after an oral dose would be in the nanograms level (18 ng.mL), which according to Tom Hale ( I just met him personally), when the mothers drug levels are at nanogram levels, the mother should be able to safely breastfeed. The peak level occurs at about 2 hours, so the mother of a two year old should certainly be able to avoid that time period, resulting in even LOWER possible breast milk levels. This is the best I can do from what is known about the pharmacokinetics of this drug. Frank J. Nice, DPA, CPHP *********************************************** To temporarily stop your subscription: set lactnet nomail To start it again: set lactnet mail (or digest) To unsubscribe: unsubscribe lactnet All commands go to [log in to unmask] The LACTNET mailing list is powered by L-Soft's renowned LISTSERV(R) list management software together with L-Soft's LSMTP(TM) mailer for lightning fast mail delivery. For more information, go to: http://www.lsoft.com/LISTSERV-powered.html