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Lactation Information and Discussion <[log in to unmask]>
Date:
Sun, 29 Apr 2007 10:56:55 EDT
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Esther quoted:
 
    "There was a modest association between increasing  serum levels of
prolactin and the risk of breast  cancer in women from the NHS.
Women in the top versus  the lowest quartile of serum prolactin had a  30%
increased risk. And these risk estimates were  similar for premenopausal
and postmenopausal women,  and for women with tumors of different
estrogen  receptor status.

For all women in the NHS and NHSII, those in  the highest quartile for
serum prolactin again had a  30% increased risk of breast cancer,
compared with  those in the lowest quartile. But the risk was altered  by
the ER status of the women's tumor.

Women in the top quartile for serum prolactin  levels had a 60% higher
risk of ER-positive breast  cancer than those in the lowest quartile.
Tworoger et  al say that their 'more complete' analysis shows  that
prolactin is 'a moderate to strong, and, likely,  independent risk factor
for breast cancer.' "
 
Notice this study says nothing about whether any of these women  lactated.  
Only their prolactin levels are noted and time of day is nt  mentioned.  So I 
have to assume they were not breastfeeding at the time of  the study or I'd 
hope it would be mentioned.
 
Perhaps having steadily higher levels of prolactin (don't they normally  rise 
during the night for everyone?) when the breasts are not functioning to  
produce milk increases the risk?
 
Mardrey Swenson
 
 
Mrdr



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