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Incorporated, a worldwide network of science museums and related institutions.
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What Don't We Know?

In a special collection of articles published beginning 1 July 2005, 
Science Magazine and its online companion sites celebrate the journal's 
125th anniversary with a look forward -- at the most compelling puzzles 
and questions facing scientists today. A special, free news feature in 
Science explores 125 big questions that face scientific inquiry over 
the next quarter-century; accompanying the feature are several online 
extras including a reader's forum on the big questions.

http://www.sciencemag.org/sciext/125th/

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