On 26-Aug-10, at 3:55 PM, allen wrote:

>
> In my opinion, the resistance that developed to OTC came about by  
> horizontal gene transfer from other, already resistant bacteria,  
> not spontaneously. However, IMO, the process was accelerated and  
> somewhat enabled by the fact that maintaining a controlling level  
> of OTC in hives at critical times is difficult.  As a result of the  
> quick fading of OTC potency over a short time under hive  
> conditions, bacteria had ample opportunity to be selected for those  
> which could tolerate OTC.
>

Hi Allen and all

The practice of feeding OTC in syrup, as was previously recommended  
by officials here,  led to inefficient control of AFB and resulting  
resistance.

Bob Darrell
Caledon Ontario
Canada
44N80W

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