>  Unlike many ‘natural’ remedies, there is a substantive database on the biological activity and toxicity of propolis indicating it may have many antibiotic, antifungal, antiviral and antitumour properties, among other attributes. Although reports of allergic reactions are not uncommon, propolis is relatively non-toxic, with a no-effect level (NOEL) in a 90-mouse study of 1400 mg/kg body weight/day 

Review of the biological properties and toxicity of bee propolis (propolis)
Food and Chemical Toxicology
Volume 36, Issue 4, 6 April 1998, Pages 347–363

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