>Druckrey and Küpfmüller inferred that if both receptor binding and the effect are irreversible, exposure time would reinforce the effect.

Hello all

Please don't misunderstand me, I think studies of this nature are indispensable for the understanding of synergistic and/or cumulative effects of carcinogens, pesticides. In fact, any sort of chemical or physical insult to organisms or systems may or may not exhibit such effects. However, they do not provide proof of anything; rather, they provide the basis for testable hypotheses. Which must then be tested in vitro and in vivo. That means field tests in the real world, otherwise all you have is a hunch. 

PLB

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