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Subject:
Xanax (Alprazolam)
From:
"Nice, Frank" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Wed, 7 Oct 1998 08:28:39 -0400
Content-Type:
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Xanax (Aprazolam)

Neonatal dose in milk is low at 3% of maternal dose which is unlikely to result
in pharmacological effect in infant.  Case report of withdrawal symptoms
(irritability, crying, sleep disturbance) in infant

Anderson PO, McGuire GG.  Neonatal aprazolam withdrawal-possible effects of
breastfeeding (letter), DICP The Annals of Pharmocotherapy 1989 Jul/Aug; 23:614.

Oo CY, Kuhn RJ, Desai N, Wright , McNamara PJ.  Pharmacokinetics in lactating
women:predicition of aprazolam transfer into milk.  Br J Clin Pharmacol 1995;
25:829-30.

Frank J. Nice. DPA, CPHP
Bethesda/Brookeville, MD
Formerly Plymouth, PA

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