Dear All,
Amoxicillin 1000mg three times a day is certainly not a problem for 
breastfeeding, and is a common dose for adults.
Amoxicillin, however, is NOT an appropriate choice for mastitis or any 
sort of breast infection, or for that matter, any sort of skin 
infection, unless the culture proves that it will cover the bacterial 
culprit. Amox generally does not cover staph aureus, which is the most 
prevalent bacteria in breast infections!!! It used to cover a good % of 
staph >30 years ago, but with the emergence of beta lactam activity of 
staph, it is just basically wrong to use it in this situation. To put it 
bluntly, it demonstrates a lack of understanding of basic infectious 
disease.
Nipple lesions and mastitic breasts should be cultured, given the 
prevalence of MRSA, and the possibility of other pathogens, such as 
beta- hemolytic strep, and group B strep.

Anne Eglash MD
Clinical Associate Professor
Dept of Family Medicine
University of Wisconsin School of Medicine and Public Health
600 N. 8th St.
Mount Horeb, WI, 53572
608-437-3064 (O)
608-437-4542 (fax)

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