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Subject:
From:
"Valerie W, McClain" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Thu, 1 Jan 2004 06:39:43 EST
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This particular patent seems to be suggesting that breastfeeding infants have
side effects--inflammatory effects--from infant formula.  Rather interesting
to think about.  Does infant formula effect the breastfed infant differently
than the infant who has always had infant formula?  It looks like Nestle is
trying to fix this "little" problem.  Funny thing is that when I was in private
practice, mothers who were doing mixed feeding always believed it was the
breastmilk/breastfeeding that was causing the problems.  I often thought that the
moms were smokers and some were (assuming it was the cigarettee byproducts in
the mom's milk causing infant irritability)  Sometimes I believed it was an
overactive MER.  But this patent makes me think that in some cases it might have
been the infant formula setting up an inflammatory reaction.  Mothers were
firm in their belief that it was their breastmilk that was causing the problem
and would quit breastfeeding.  In calls back to these moms, they would say that
the baby was much better.  I assumed that they just wanted to quit
breastfeeding.  But maybe certain ingredients in artificial milks create problems in the
breastfed infant that are not created in the exclusively formula-fed infant?
Valerie W. McClain, IBCLC

http://www.uspto.gov/patft/index.html
patent # 6420156
"Purified proteolytic enzyme and method of purification"
inventor:  Braun et al.
assignee:  Nestec SA
filed 1998

"FIELD OF THE INVENTION

The invention relates to a purified proteolytic enzyme and to a method of
purifying a proteolytic enzyme, in particular trypsin.

BACKGROUND ART

Commercial proteases, in particular commercial trypsin, even after
purification by a special treatment, for example by double crystallization, contains
residual lipases, in particular phospholipase A.sub.2, which is particularly
resistant to the heat deactivation to which protease is subjected after its use in
a hydrolysis process.

Trypsin is commonly used in the manufacture of protein hydrolysates intended
in particular to enter into the composition of infant products. To incorporate
the protein portion into a finished product, for example an infant milk, any
residual lipolytic enzymatic activity resulting from the protein hydrolysate
must be removed. This is necessary in order to avoid the appearance of products
of degradation of lecithin which is added to the final formula for
technological reasons, for example to enhance the wettability of powders, into
lysolecithin, in particular during storage. Such breakdown products may manifest
themselves both in liquid products and in powders by the appearance of stability or
organoleptic defects, for example spots, poor taste, or by their toxicity
leading to side effects, for example of an inflammatory type in breastfeeding
infants. "




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