Not a lot known about this one. However, it is not the only antidepressant on the market. What about sertraline, paroxetine. If it has to be venlafaxine, what about observing baby, doing milk and/or baby blood levels? There are no known effects with this drug in the nursing infant, but there could be, true. There *are* known effects to not breastfeeding (including negative effects on the baby's brain, which is the concern with the use of these types of drugs). Jack Newman, MD, FRCPC