When questioning whether ibuprofen is decreasing milk supply, the question must be asked, why is she taking ibuprofen in the first place? Usually that''s for some type of pain. Chronic pain causes chronic release and sometimes exhaustion of the adrenals and adrenalin response. Adrenaline counteracts the action of smooth muscle (decreases digestive rates, slows contractions in labor, slows MER) Could not the true problem be whatever is causing the pain? Treat the cause of the pain, maybe chiropractic, massage therapy, physical therapy, etc. and you don't have the adrenal response plus don't need pain or antiinflammatory meds. You have better MER, better breast emptying and the autocrine response picks up and breast output increases. Remember, the true cause of a problem may not be the obvious surface cause but a deeper root problem so dig deeper and pull out the root if you can! Jane Kershaw @ [log in to unmask]