<< CMAJ . September 28, 2004; 171 (7). 

Health And Drug Alerts
Domperidone for lactating women 
Orlando P. da Silva* and David C. Knoppert 

Reason for posting: Domperidone has been widely used as a motility and
antiemetic agent. In oral form it is also used off label to improve
lactation in breast-feeding women...
continued, goto  Canadian Medical Association Journal article on
Highwire,
 http://makeashorterlink.com/?F4212167B >>


Thanks, Arly! I traveled via the link you provided and was able to download the article as a pdf file. BTW, this letter was printed in response:

<< Have they studied it properly ?	29 September 2004
	   
Dr. A. LakKumar Fernando, Consultant Paediatrician, General Hospital, Chilaw, Sri Lanka 
Recommendations on domperidone in lactating women is based on the effects of IV high dose. As a Consultant Paediatrician I have asked(prescribed)well over 1000 women to take Domperidone at a dose of 10mg t.i.d for 14 days in order to help breast feeding(to increase supply of breast milk) and think it works well for many. I have never come across a single women developing any symptoms suggestive of arrhythmias with this dose. I know of many colleagues of mine who do the same and they too have a similar experience. In Sri Lanka over 95% of babies will be breast fed within the 1st month and about 70% will continue to breast feed even at 6 months. For a few who have initial problems domperidone help and should we deprive those women and their babies of such benifits? It is well known that paracetamol is fatally toxic at high doses even when taken orally but that does not prevent thousands taking it at the proper dose for pain or fever. I recently learnt that FDA approves the use of Polycarbonate Plastic Bottles to feed infants though there are concerns about its safety. There FDA appears to 'assume safty and ask to prove harm by plastic bottles' but act differently when it comes to breast feeding. 

Dr. A LakKumar Fernando MBBS(SL),DCH,MD(Paed),MRCP(UK),MRCPCH(UK) Consultant Paediatrician, General Hospital, Chilaw, Sri Lanka. 

Conflict of Interest: None declared >>	

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