Rachel, Please send me more information on the PKU test in Norway. I am a 
hospital-based lactaion consultant in Maryland,USA. The PKU test are done 
twice here. at 48 hours and then 2 weeks. Our NICU babies are stuck  more 
than that for the PKU. Any clinical studies and test would be so 
appreciated. Thank you, Deb Dixon @[log in to unmask]
----- Original Message ----- 
From: "Rachel Myr" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Friday, November 11, 2005 6:15 AM
Subject: Timing of PKU test


> Don't know what kind of lab technology is in use for PKU screening in 
> Ohio,
> or anywhere else, but in Norway we went from serum testing to whole blood
> testing a couple of years ago.  What food the baby has been getting is
> irrelevant, as is whether they have started gaining or stooling or 
> whatever;
> the test is valid if done after 60 hours of age, because it relies on
> metabolic changes that occur in people with PKU no matter what.  Optimal
> timing is between 60 and 72 hours.  A week is 4 days longer than 
> necessary,
> but better late than never.
>
> The only other screening test we do at present is for congenital
> hypothyroidism, which could be done on cord blood, but since the same lab
> analyzes both tests, the blood is collected at the earliest convenient 
> time
> after 60 hours for the sake of effectiveness and simplicity.  I have 
> picked
> up cases of both conditions in babies I never would have suspected of 
> having
> a problem based on their clinical appearance on day 3 or 4.
>
> Rachel Myr
> Kristiansand, Norway
>
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