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Subject:
From:
Nikki Lee <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Fri, 19 Oct 2007 12:30:44 -0400
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Dear Friends:

So wonderful to have an anesthesiologist in our LACTNET world!

Rentanyl is?linked to reduced breastfeeding. "The impact of intrapartum analgesia on infant feeding" Jordan et al. BJOG 2005; 112(7):927-934.

Conclusions "A dose-response relationship between fentanyl and artificial feeding has not been reported elsewhere. When well-established determinants of infant feeding are accounted for, intrapartum fentany may impede establishment of breastfeeding, particularly at higher doses."

Back in the 1970s, Demerol (meperidine or pethidine) was shown to reduce sucking, as the metabolite is bioactive and takes days for a baby to clear.

This all means that babies need to be left s2s after delivery until they've finished their cluster of breastfeeding bouts and gone into deep sleep.

warmly,



Nikki Lee




From:    Sarah Reece-Stremtan <[log in to unmask]>

 Fentanyl may very well have some effect on an infant's
behavior immediately following birth, but it is very rapidly metabolized =
and
I would think that we would see much more bradycardia and respiratory
depression in all these otherwise normal infants, two "side effects" that=
 we
see all the time when giving fentanyl IV but that are not necessarily
worrisome (depending on the extent!)



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