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Date: | Wed, 20 Jul 2005 20:29:29 -0700 |
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CMAJ . September 28, 2004; 171 (7).
Health And Drug Alerts
Domperidone for lactating women
Orlando P. da Silva* and David C. Knoppert
Reason for posting: Domperidone has been widely used as a motility and
antiemetic agent. In oral form it is also used off label to improve
lactation in breast-feeding women. Intravenous domperidone has been
withdrawn from the market worldwide because of reports of cardiac
arrhythmia and sudden death in patients with malignant disease who
received relatively high intravenous doses of the drug for nausea and
vomiting induced by cytotoxic therapy...
... Domperidone has been approved for oral use in Canada and worldwide
as a motility agent with an excellent safety record...
...Lactating women with decreased milk supply who are unresponsive to
nonpharmacologic measures to enhance lactation, including counselling,
relaxation techniques and mechanical expression, should continue to
consider domperidone at antiemetic doses.
continued, goto Canadian Medical Association Journal article on
Highwire,
http://makeashorterlink.com/?F4212167B
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